Breast Cancer-derived PDGFB Remodels the CNS Vascular Niche to Promote Brain, Spinal and Leptomeningeal Metastasis
Nathaniel S Grabinski, Jesse J. Reardon, Sajita Shah…·Gina M. Sizemore
This study shows that breast cancer-derived PDGFB remodels the CNS vascular niche, promoting brain, spinal, and leptomeningeal metastasis through multiple mechanisms.