BiophysicsbioRxivPreprint
Millisecond nonlinear state changes during droplet coalescence identify therapeutic-antibody developability liabilities
Alexander N. St John, Jack Holland, Elizabeth Suk‐Hang Lam…·Shamit Shrivastava
The paper uses a liquid state machine to analyze antibody coalescence dynamics, identifying a biophysical liability linked to gel-like stiffening during droplet merging.
DOI 10.64898/2026.05.06.723251