Author

Nikoleta G. Tsvetanova

Duke UniversityORCID 0000-0001-6533-187XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

Katherine L. HalliD· 2 shared Matthew J. KlaueriD· 2 shared Caitlin A. D. JaglaiD· 1 shared Malarie E Schexnider· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

4 top collaborators · 5 mutual co-author links

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2 shared papersCell Biology

Katherine L. HallORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintAug 26, 2025

GPCR endocytosis rewires neuronal gene expression and cellular architecture

Katherine L. Hall, Matthew J. Klauer, Malarie E Schexnider, Nikoleta G. Tsvetanova

This study shows that beta-2 adrenergic receptor activation on endosomes drives structural changes in neurons through transcriptional and translational pathways.

DOI 10.1101/2025.08.26.672159

humanbulk RNA-seq

𝕏 PostBluesky

Cell BiologyProceedings of the National Academy of SciencesPeer-reviewedFeb 18, 2025

Extensive location bias of the GPCR-dependent translatome via site-selective activation of mTOR

Matthew J. Klauer, Katherine L. Hall, Caitlin A. D. Jagla, Nikoleta G. Tsvetanova

This study identifies translational regulation by GPCRs, showing that beta2-AR activation selectively induces translation of TOP motif-containing genes via endosomal mTOR.

8 citations

humanRibo-seq

𝕏 PostBluesky