Author

Yuan Yan Sin

University of GlasgowORCID 0000-0001-6537-5266Unclaimed ORCID profile · follow to get notified of new preprints

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Yuan Yan Sin1 paper · University of Glasgow;

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:human· 1

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Alina ZorniD· 1 shared Bria O’Gorman· 1 shared Chih-Jung Chang· 1 shared Connor M. BlairiD· 1 shared Danny T. Huang· 1 shared Elka KyurkchievaiD· 1 shared George S. Baillie· 1 shared Gillian Lappin· 1 shared

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2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Alina ZornORCID

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1 paper

Recent·Most cited

Cancer BiologyMolecular Therapy OncologyPeer-reviewedAug 6, 2025

Targeting MDM2 homodimer and heterodimer disruption with DRx-098D in TP53 wild-type and mutant cancer cells

Sean F Cooke, Thomas A. Wright, Gillian Lappin…·Connor M. Blair

This study shows DRx-098D, a peptide disrupting MDM2 dimerisation, effectively inhibits cancer cell growth in TP53 wild-type and mutant cell lines, outperforming Idasanutlin in TP53 null cells.

2 citations

humanexperimental assay

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