BioengineeringbioRxivPreprint
A Modular Bioinstructive Platform for Additive-Free, Topography-Driven Stem Cell Differentiation and Patterning
Fatmah I. Ghuloum, Leo A. H. Zeef, Lee A. Stevens…·Mahetab H. Amer
This paper introduces a topography-driven platform for stem cell differentiation without biochemical cues, showing it induces osteogenesis through mechanotransduction and Hedgehog signaling.