Leo A. H. Zeef

This study shows that activating pattern recognition receptors in tumors enhances stem cell-like memory CD8 T cells, improving antitumor immunity when combined with radiation in lung and bladder cancer models.

This study uses a multi-omics approach to analyze regional differences in cardiac responses to radiation, identifying distinct molecular and structural changes in different heart regions.

This paper introduces a topography-driven platform for stem cell differentiation without biochemical cues, showing it induces osteogenesis through mechanotransduction and Hedgehog signaling.

The paper investigates transcriptional and morphological changes in three strains of Maudiozyma bulderi at low pH, identifying genes involved in acidophilic adaptation.

The paper analyzes clinical and mechanistic data from individuals with ACTB/ACTG1 variants to identify distinct disease phenotypes and molecular mechanisms of non-muscle actinopathies.

This study uses HNF1B mutant kidney organoids to reveal molecular and physiological defects in dysplastic kidney malformations and identify potential therapeutic targets.

This study investigates how hybridisation in Saccharomyces species affects antifungal drug resistance by identifying QTLs and potential causal genes involved in resistance to fluconazole, micafungin, and flucytosine.

The paper investigates how mitochondrial DNA retention in yeast hybrids affects nuclear gene transcription and fitness across different environments.