Heather M. Karner

The paper introduces ecCLIP for high-resolution RBP binding maps and Pythia for structure-aware RNA-protein interaction modeling, improving RNA half-life prediction and variant effect assessment.

The paper identifies a metastasis-suppressive regulatory axis involving RBMS3 and TXNIP by analyzing mRNA stability in breast cancer using a deep-learning framework.

The paper investigates the functional conservation of lncRNA JPX across species despite sequence and structural divergence, showing it can functionally complement Jpx in mouse cells.