Jerome Samir

This study identifies clonal IEL expansion and epithelial remodelling in RCD1 using single-cell multi-omics, showing distinct immune and epithelial states compared to ACD.

SCARCE identifies rare somatic mutations in single-cell data by comparing variant frequencies across cell subpopulations, successfully detecting variants in as few as 10 cells.

VDJView is a tool for analysing immune single-cell multi-omics data, integrating gene expression, immune receptors, and clinical metadata to identify antigen-specific gene signatures and clonal expansions.

VDJPuzzle 2.0 reconstructs full-length B-cell receptor sequences from scRNA-seq with high accuracy, validated against Sanger sequencing.