Andrew Calcino

This study identifies clonal IEL expansion and epithelial remodelling in RCD1 using single-cell multi-omics, showing distinct immune and epithelial states compared to ACD.

This study shows that pulmonary delivery of ESAT-6-secreting BCG strains improves safety and protection against TB in immunocompromised mice, independent of adaptive immunity.

The paper detects structural variants in single mollusc genomes, revealing widespread hemizygosity and pan-genome features across the clade.

The paper identifies heteroplasmy and repeat expansions in the mitochondrial genome of the quagga mussel, suggesting plant-like recombination-based error correction mechanisms.

The paper sequenced the quagga mussel genome to identify evolutionary adaptations for freshwater tolerance, finding expanded aquaporin genes and osmoregulatory structures involved in embryonic osmoregulation.

The paper identifies diverse RNAi components in non-bilaterian animals, revealing unique miRNA, piRNA, and endo-siRNA repertoires compared to bilaterians.