Author

Kelly L. Bolton

Memorial Sloan Kettering Cancer CenterORCID 0000-0001-6584-3357Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Genomics· 2 Genetics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 3 Approach:statistical model· 3 Research Focus:variant effect prediction· 2 Assay:whole-exome sequencing· 2 Approach:benchmark study· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:GWAS / association mapping· 1

Frequent Co-Authors

Benjamin L. EbertiD· 2 shared Elli PapaemmanuiliD· 2 shared Elsa BernardiD· 2 shared Gunes GundemiD· 2 shared Juan E. Arango· 2 shared Juan Santiago Medina-MartineziD· 2 shared Max Fine LevineiD· 2 shared Minal A. Patel· 2 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersGenomics

Benjamin L. EbertORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

GenomicsbioRxivPreprintDec 21, 2023

The age-related deceleration of clonal haematopoiesis in 420,000 healthy adults

Hamish A J MacGregor, Duc Tran, Kelly L. Bolton…·Jamie R. Blundell

The paper analyzes age-related changes in clonal haematopoiesis (CH) using whole exome data from 420,000 UK Biobank participants, finding a deceleration of clonal expansion with age.

4 citations

humanwhole-exome sequencing

𝕏 PostBluesky

GenomicsNature MedicinePeer-reviewedAug 3, 2020

Implications of TP53 Allelic State for Genome Stability, Clinical Presentation and Outcomes in Myelodysplastic Syndromes

Elsa Bernard, Yasuhito Nannya, Robert Paul Hasserjian…·Elli Papaemmanuil

The paper examines TP53 allelic states in MDS patients, finding that bi-allelic targeting is linked to worse outcomes, while mono-allelic targeting does not differ from wild-type patients.

648 citationstop 1%

humanDNA methylation

𝕏 PostBluesky

GeneticsbioRxivPreprintNov 20, 2019

Oncologic Therapy Shapes the Fitness Landscape of ClonalHematopoiesis

Kelly L. Bolton, Ryan N. Ptashkin, Teng Gao…·Elli Papaemmanuil

The paper shows oncologic therapy increases clonal hematopoiesis with DDR mutations, which predicts risk of therapy-related myeloid neoplasms.

20 citations

humanwhole-exome sequencing

𝕏 PostBluesky