Yuji Nishiike

This study shows brain-derived estrogens enhance male-typical behaviors in medaka by boosting androgen receptor signaling, even though androgens can act directly in other vertebrates.

The paper identifies cholecystokinin as the FSH-releasing hormone (FSH-RH) in medaka, challenging the solo GnRH model and proposing a dual GnRH model in vertebrates.

This study shows that neuropeptide B mediates female sexual receptivity in medaka fish in a female-specific and reversible manner through estrogen-dependent regulation.