Author

Umapriyatharshini Rajagopalan

Institute of Biochemistry, Molecular Biology and BiotechnologyORCID 0000-0001-6587-484XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Pharmacology & Toxicology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2

Frequent Co-Authors

Kanishka Sithira SenathilakeiD· 2 shared Nirwani Natasha SeneviratneiD· 2 shared Sameera R. SamarakooniD· 2 shared Dinara S. Gunasekara· 1 shared Dipun N. PereraiD· 1 shared Dipun Nirmal Perera· 1 shared Duvinika Chalani Senavirathna· 1 shared Fathima T. MuhinudeeniD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersPharmacology & Toxicology

Kanishka Sithira SenathilakeORCID

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2 papers

Recent·Most cited

In vitro anti-cancer properties of a commercially available polyherbal nutraceutical (Vernolac) capsule on cancer stem cell-like (NTERA-2 cl.D1) cells.

Poorni Chanuka Rathnayake, Duvinika Chalani Senavirathna, Matheen Muhammadh Milhan, Sandani De Vass Gunawardane, Nirwani Natasha Seneviratne, Dipun Nirmal Perera, Umapriyatharshini Rajagopalan, Kanishka Sithira Senathilake, Sameera R. Samarakoon

This study evaluates the anti-cancer effects of Vernolac extract on NTERA-2 cl.D1 cancer stem-like cells, showing significant cytotoxicity and apoptosis induction with minimal impact on non-cancerous cells.

Egyptian Journal of Basic and Applied Sciences · Dec 2, 2025Peer-reviewedPharmacology & Toxicology

Anti-proliferative and Apoptosis Inducing Effect of Thymoquinone in Human Teratocarcinomal (NTERA-2) Cancer Stem-Like Cells

Rajitha Kalum Rathnayaka, Fathima T. Muhinudeen, Nirwani Natasha Seneviratne, Dipun N. Perera, Shalini K. Wijerathne, Umapriyatharshini Rajagopalan, Kanishka Sithira Senathilake, Dinara S. Gunasekara, Kamani Hemamala Tennekoon, Sameera R. Samarakoon

This study evaluates thymoquinone's anti-proliferative and pro-apoptotic effects on NTERA-2 cancer stem-like cells and PBMCs, showing dose- and time-dependent inhibition of proliferation and increased apoptosis.

bioRxiv · Sep 8, 2025 · PreprintPharmacology & Toxicology