Cancer BiologybioRxivPreprint
Enhanced Radio-sensitization of Glioblastoma using a Dendrimer-Based Metformin Nano-formulation through Direct Tumor Suppression and Indirect Immune Modulation
Sadaf Mahfooz, Fei Wang, Ghanbar Mahmoodi Chalbatani…·Chi Zhang
This study develops a dendrimer-based metformin nano-formulation (P4-MET) that enhances GBM treatment by improving drug delivery, modulating ferroptosis pathways, and synergizing with radiotherapy.
DOI 10.64898/2026.05.12.724405