Author

Eduardo Tolosa

Consorci Institut D'Investigacions Biomediques August Pi I SunyerORCID 0000-0001-6608-3038Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:imaging· 1 Assay:proteomics· 1

Frequent Co-Authors

Adriana CortésiD· 1 shared Alícia GarridoiD· 1 shared Almudena Sánchez‐GómeziD· 1 shared Ana CámaraiD· 1 shared Ángel RayaiD· 1 shared Antonella ConsiglioiD· 1 shared Cèlia PainousiD· 1 shared Enrique SantamaríaiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperNeuroscience

Adriana CortésORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintDec 9, 2025

Phospho-signalling deregulation of the mTOR pathway in fibroblasts from LRRK2 Parkinson s patients

Rodolfo Alejandro, Joaquín Fernández‐Irigoyen, Pares Guillem…·Mario Ezquerra

This study identifies mTOR pathway deregulation in fibroblasts from LRRK2 Parkinson's patients through proteomic and phospho-proteomic analysis.

DOI 10.64898/2025.12.05.692089

humanproteomics

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Cell BiologyCommunications BiologyPeer-reviewedAug 12, 2025

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LRRK2-mutant microglia and neuromelanin synergize to drive dopaminergic neurodegeneration in an iPSC-based Parkinson's disease model

Lucas Blasco-Agell, Meritxell Pons‐Espinal, Veronica Testa…·Antonella Consiglio

LRRK2 G2019S iPSC-derived microglia exposed to neuromelanin, but not α-synuclein fibrils, reduce healthy dopaminergic neuron numbers in co-culture; ivermectin prevents this, and post-mortem midbrain supports it.

16 citationstop 1%

humanimaging

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