The paper screens phytochemicals from Ficus hispida fruit for prostate cancer treatment using in silico tools and MD simulations, identifying three compounds with potential therapeutic properties.

DOI 10.1101/2023.06.04.543596

statistical modeldrug response / drug discovery

𝕏 PostBluesky

BioinformaticsNetwork Modeling Analysis in Health Informatics and BioinformaticsPeer-reviewedNov 7, 2021

In silico chemical profiling and identification of neuromodulators from Curcuma amada targeting Acetylcholinesterase

Md. Chayan Ali, Yeasmin Akter Munni, Raju Das…·Md. Abdul Hannan

This study identifies neuromodulators from Curcuma amada targeting Acetylcholinesterase using in silico methods, showing drug-likeness and potential therapeutic effects for neurodegenerative disorders.

5 citations

statistical modelsimulation

𝕏 PostBluesky

NeurosciencePhytomedicinePeer-reviewedNov 19, 2020

Natural LXRβ agonist stigmasterol confers protection against excitotoxicity after hypoxia-reoxygenation (H/R) injury via regulation of mitophagy in primary hippocampal neurons

Md. Nazmul Haque, Md. Abdul Hannan, Raju Dash…·Il Soo Moon

This study shows that stigmasterol protects hippocampal neurons from hypoxia-reoxygenation injury by inducing mitophagy through LXRβ activation.

57 citationstop 4%

ratstatistical model

𝕏 PostBluesky