Reactive Bergmann glia play a central role in Spinocerebellar ataxia inflammation via the JNK pathway
Chandrakanth Reddy Edamakanti, Vishwa Mohan, Puneet Opal
The paper identifies a JNK-dependent signaling pathway in Bergmann glia that drives inflammation in spinocerebellar ataxia, showing that inhibiting this pathway improves disease symptoms.
bioRxiv · Jun 29, 2022 · PreprintNeuroscience