Toshifumi Yokota

This paper demonstrates that NEV3, an EV-anchoring nanobody, enables in situ loading of proteins onto circulating extracellular vesicles and redirects them to specific tissues in vivo.

eSkip2 identifies effective exon-skipping ASO target regions by integrating genomic context and splicing perturbations, outperforming exon-restricted models in prioritizing active regions.