Author

Zdeňka Ellederová

Czech Academy of SciencesORCID 0000-0001-6695-6345Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Organism:plant (other)· 1

Frequent Co-Authors

Jan MotlíkiD· 2 shared Miroslav VeithiD· 2 shared Taras ArdaniD· 2 shared Andrea BähriD· 1 shared Andrea FischeriD· 1 shared Andreas BlutkeiD· 1 shared Andreas KlingliD· 1 shared Andreas WiestiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersMolecular Biology

Jan MotlíkORCID

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintJul 3, 2026

Gene Supplementation of MYO7A or activation of Myo7b for treatment of Usher syndrome 1B

David Manuel Mittas, Dina Yehia Otify, Zoran Gavrilov…·Elvir Bećirović

This study evaluates gene supplementation of MYO7A via dual AAVs and CRISPR/Cas activation of Myo7b in animal models and human retinal organoids to treat Usher syndrome 1B.

DOI 10.64898/2026.07.02.736025

mousehuman

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GeneticsEMBO Molecular MedicinePeer-reviewedMar 7, 2022

Early Disruption of Photoreceptor Cell Architecture and Loss of Vision in a Humanized Pig Model of Usher Syndrome

Sophia Grotz, Jessica Schäfer, Kirsten A. Wunderlich…·Nikolai Klymiuk

This study creates a humanized pig model of Usher syndrome type 1, showing disrupted photoreceptor architecture and vision loss, and validates gene therapy approaches.

49 citations

plant (other)experimental assay

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