Kirsten A. Wunderlich

The paper identifies the glucocorticoid receptor as a master regulator of Muller cell gliosis in diabetic retinopathy and shows that increasing GR expression can improve retinal function.

The paper identifies VAMP5 as a SNARE component in extracellular vesicles released by retinal Muller glia and shows differences in their secretomes compared to neurons.

The paper investigates harmonin expression and localization in human retinas to understand USH1C pathophysiology and potential gene therapy approaches.

This study creates a humanized pig model of Usher syndrome type 1, showing disrupted photoreceptor architecture and vision loss, and validates gene therapy approaches.

The paper identifies 285 candidate ciliary genes using integrated genomic, proteomic, and transcriptomic data, validated by experimental evidence and creating a resource for ciliopathy research.