NeurosciencebioRxivPreprint
A transient protein folding response targets aggregation in the early phase of TDP-43-mediated disease
Rebecca San Gil, Dana Pascovici, Juliana Venturato…·Adam K. Walker
This study identifies a transient protein folding response in early TDP-43 disease that reduces aggregation, with DNAJB5 as a protective factor, and shows proteomic similarities between mouse and human TDP-43 proteinopathies.
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