Author

Jared J. Fradette

The University of Texas MD Anderson Cancer CenterORCID 0000-0001-6712-2860Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Amrita BaruaiD· 1 shared Bhagya Shree ChoudharyiD· 1 shared David H. PengiD· 1 shared Don Lynn GibbonsiD· 1 shared Jing WangiD· 1 shared Lixia DiaoiD· 1 shared Samrat T. KunduiD· 1 shared Sofia Garza· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperCancer Biology

Amrita BaruaORCID

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1 paper

Recent·Most cited

Cancer BiologybioRxivPreprintDec 25, 2025

PDK1 and YAP1/TEAD signaling drive acquired KRAS inhibitor resistance in KRAS-mutant non-small cell lung cancer.

Amrita Barua, Samrat T. Kundu, Sofia Garza…·Don Lynn Gibbons

This study identifies PDK1 and YAP1/TEAD signaling as drivers of acquired resistance to KRAS inhibitors in NSCLC and suggests their co-targeting as a potential therapeutic strategy.

DOI 10.64898/2025.12.22.696060

humanbulk RNA-seq

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