Author

Samrat T. Kundu

The University of Texas MD Anderson Cancer CenterORCID 0000-0002-0117-6986Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Amrita BaruaiD· 1 shared Bhagya Shree ChoudharyiD· 1 shared David H. PengiD· 1 shared Don Lynn GibbonsiD· 1 shared Jared J. FradetteiD· 1 shared Jing WangiD· 1 shared Lixia DiaoiD· 1 shared Sofia Garza· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperCancer Biology

Amrita BaruaORCID

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1 paper

Recent·Most cited

PDK1 and YAP1/TEAD signaling drive acquired KRAS inhibitor resistance in KRAS-mutant non-small cell lung cancer.

Amrita Barua, Samrat T. Kundu, Sofia Garza, Jared J. Fradette, Bhagya Shree Choudhary, David H. Peng, Lixia Diao, Jing Wang, Don Lynn Gibbons

This study identifies PDK1 and YAP1/TEAD signaling as drivers of acquired resistance to KRAS inhibitors in NSCLC and suggests their co-targeting as a potential therapeutic strategy.

bioRxiv · Dec 25, 2025 · PreprintCancer Biology