BioinformaticsJACS AuPeer-reviewed
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PARAS: high-accuracy machine-learning of substrate specificities in nonribosomal peptide synthetases
Barbara R. Terlouw, Chuan Huang, David Meijer…·Marnix H. Medema
Random forest predictors PARAS and PARASECT, trained on 3,653 curated adenylation domains, outperform earlier NRPS substrate predictors and correctly assigned L-Trp to an unusual tryptopeptin synthetase domain.
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