Line S. Löken

The paper shows that soft tactile stimulation activates parabrachial circuits, including CGRP neurons, which are typically linked to aversion, indicating these pathways may encode affective significance of touch.

The paper investigates the distribution and physiological properties of C-tactile afferents in human arm and leg nerves, finding they are more sparse in the lower leg and insensitive to menthol and histamine.

The paper identifies a new population of CGRP-expressing interneurons in the spinal cord dorsal horn that contribute to mechanical hypersensitivity after nerve injury.