Bart M. J. De Spiegeleer

This study investigates the ability of the quorum sensing peptide PapRIV to activate BV-2 microglia and cross biological barriers, showing in vitro activation and in vivo presence.

The paper demonstrates that the quorum sensing peptide EntF* from gut microbiota promotes colorectal cancer metastasis in mice, identifying it as a novel mediator of microbiome-host interaction.

This paper describes an optimized cloning-based bisulfite sequencing strategy for locus-specific methylation analysis, focusing on quality control and a pooled cloning approach to improve efficiency.