Dale Chaput

The paper identifies citrullination of tau as a novel posttranslational modification in Alzheimer's disease and tauopathy models, showing its association with disease progression.

This study introduces ToxoFUCCI sensors to analyze the complex cell cycle of Toxoplasma gondii, revealing an unusual composite cell cycle phase with overlapping stages.

This paper introduces a new N-terminomic method, TAGS-CR, to identify substrates of the S. aureus V8 protease in human neutrophils, revealing 350 targets that modulate neutrophil function and immune response.

This study identifies citrullination as a novel irreversible post-translational modification of TDP-43 linked to structural changes, aggregation, and pathology in TDP-43 proteinopathies.