Author

Akshay Chenna

Indian Institute of Technology DelhiORCID 0000-0001-6830-3751Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 3

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Assay:proteomics· 2 Research Focus:benchmarking· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:protein structure· 1 Approach:statistical model· 1

Frequent Co-Authors

Gaurav GoeliD· 2 shared Aaron L. FelleriD· 1 shared Abel GurungiD· 1 shared Ajasja LjubetičiD· 1 shared Alberto Perez· 1 shared Alejandro Diaz· 1 shared Alex M. AbeliD· 1 shared Alia Clark‐ElSayediD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersBioinformatics

Gaurav GoelORCID

Author profile →

3 papers

Recent·Most cited

Validation and analysis of 12,000 AI-driven CAR-T designs in the Bits to Binders competition

Clayton W. Kosonocky, Alex M. Abel, Aaron L. Feller, Amanda Cifuentes Rieffer, Phillip R. Woolley, Jakub Lála, Delbert S. Barth, Tynan Gardner, Bits to Binders Competitors, Daniel Acosta, Stefano Angioletti‐Uberti, Vinayak Annapure, Neil Anthony, Rana A Barghout, Max Beining, , Rohit Satija

The paper validates and analyzes 12,000 AI-designed CAR-T binders from a global competition, identifying successful designs and factors improving their performance.

Molecular Systems Biology · Oct 8, 2026Peer-reviewedBioinformatics

Protein Language Model Based Structure-guided Antibody Screening for Disordered Protein Targets

Akshay Chenna, Prasoon Priyadarshi, Keshav Kolluru, Saurabh Singal, Gaurav Goel

The paper develops a computational pipeline using a protein language model and deep learning to screen high-affinity antibodies for a disordered protein target without prior binder information.

bioRxiv · Jun 21, 2025 · PreprintBioinformatics

Template-based design of peptides to inhibit SARS-CoV-2 RNA-dependent RNA polymerase complexation.

Akshay Chenna, Wajihul Hasan Khan, Rozaleen Dash, Anurag Singh Rathore, Gaurav Goel

The paper designs peptides to inhibit SARS-CoV-2 RdRp complexation by targeting the nsp7-nsp12 interface using structural bioinformatics and molecular dynamics.

bioRxiv · Jan 24, 2022 · PreprintBioinformatics