Author
The University of Texas at AustinORCID 0000-0001-9602-4231Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Dylan M. Brown, Alia Clark‐ElSayed, Taylor M. Mott…·Andrew D. Ellington
This study designs and characterizes peptide-responsive biosensors that regulate gene expression using intracellular peptide effectors and transcription factors in vitro and in vivo.
Clayton W. Kosonocky, Alex M. Abel, Aaron L. Feller…·Rohit Satija
The paper validates and analyzes 12,000 AI-designed CAR-T binders from a global competition, identifying successful designs and factors improving their performance.
Alia Clark‐ElSayed, Ethan Creed, Kaila E. Nayvelt, Andrew D. Ellington
The paper compares LigandMPNN and directed evolution for redesigning the effector-binding site of the RamR transcription factor, finding limited overlap between the two methods' results.