Wenjun Xiong

This study shows that inhibiting Notch signaling and forcing cell cycle re-entry in Müller glia promotes their reprogramming into neurons in uninjured mouse retina.

This study demonstrates that lipid nanoparticle-mediated CRISPR/Cas9 delivery efficiently edits genes in the trabecular meshwork of mice, inducing glaucoma-like features.

This study shows that overexpressing cyclin D1 and knocking down p27kip1 in mouse Müller glia using AAV enables controlled cell cycle reactivation without uncontrolled proliferation.