EchinoDB is updated to include new RNA-seq and genomic data, improved search features, and cloud-based infrastructure for echinoderm genomic and transcriptomic data.

BMC Genomic Data · Oct 23, 2022Peer-reviewedBioinformatics

Draft Genome of the Sea Cucumber Holothuria glaberrima, a model for the study of regeneration

Joshua G. Medina-Feliciano, S Pirro, José E. García‐Arrarás, Vladimir S. Mashanov, Joseph F. Ryan

This paper presents the first draft genome of the sea cucumber Holothuria glaberrima, demonstrating its utility for studying regeneration and other genetic research.

Frontiers in Marine Science · Apr 15, 2021Peer-reviewedGenomics

Active Notch Signaling is Required for Arm Regeneration in a Brittle Star

Vladimir S. Mashanov, Jennifer Akiona, Maleana Khoury, Jacob W. Ferrier, Robert W. Reid, Denis Jacob Machado, Olga R. Zueva, Daniel A. Janies

This study shows Notch signaling is essential for arm regeneration in brittle stars and identifies its role in regulating extracellular matrix, cell migration, and transposable elements.

PLoS ONE · May 12, 2020Peer-reviewedDevelopmental Biology

The Complex Simplicity of the Brittle Star Nervous System

Olga R. Zueva, Maleana Khoury, Thomas Heinzeller, Daria Mashanova, Vladimir S. Mashanov

This paper provides a detailed anatomical description of the brittle star nervous system, including nomenclature standardization, 3D modeling, and identification of cell-type markers.

Frontiers in Zoology · Feb 1, 2018Peer-reviewedNeuroscience