Olga R. Zueva

This paper introduces a chemically inducible gene editing system in the sea star Patiria miniata using Tet-ON and CRISPR, enabling inducible gene alteration in transgenic cell populations for the first time in echinoderm biology.

This study shows that sea star larval nervous system regeneration involves sox2 lineage respecification and partial reuse of developmental gene regulatory networks.

The paper compares developmental GRNs to show how novelty is incorporated while maintaining network stability during early development.

This study shows Notch signaling is essential for arm regeneration in brittle stars and identifies its role in regulating extracellular matrix, cell migration, and transposable elements.

The paper analyzes sea star larval regeneration to identify conserved molecular processes of whole-body regeneration across metazoans.

This paper provides a detailed anatomical description of the brittle star nervous system, including nomenclature standardization, 3D modeling, and identification of cell-type markers.