Single-cell epigenomic identification of inherited risk loci in Alzheimer's and Parkinson's disease
M. Ryan Corces, Anna Shcherbina, Soumya Kundu, Michael J. Gloudemans, Laure Frésard, Jeffrey M. Granja, Bryan H. Louie, Tiffany Y. Eulalio, Shadi Shams, S. Tansu Bagdatli, Maxwell R. Mumbach, Boxiang Liu, Kathleen S. Montine, William James Greenleaf, Anshul Bharat Kundaje, , Thomas Jude Montine
The paper uses single-cell epigenomic data to identify functional SNPs associated with Alzheimer's and Parkinson's disease, revealing novel gene-disease associations and regulatory mechanisms.
Nature Genetics · Oct 26, 2020Peer-reviewedGenomics