Author

Steven G. Fagan

Trinity College DublinORCID 0000-0001-6942-7393Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Ana Belén López-RodrígueziD· 1 shared Anouchka Jasmine LewisiD· 1 shared Arshed NazmiiD· 1 shared Carol MurrayiD· 1 shared Colm M. CunninghamiD· 1 shared Dáire HealyiD· 1 shared Delphine BocheiD· 1 shared Edel HennessyiD· 1 shared

Activity by Year

2021-2021 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Ana Belén López-RodríguezORCID

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1 paper

Recent·Most cited

NeuroscienceAlzheimer s & DementiaPeer-reviewedJun 3, 2021

Microglial and Astrocyte priming in the APP/PS1 model of Alzheimer’s Disease: increased vulnerability to acute inflammation and cognitive deficits

Ana Belén López-Rodríguez, Edel Hennessy, Carol Murray…·Colm M. Cunningham

This study shows that in the APP/PS1 AD mouse model, microglia and astrocytes are primed to produce exaggerated inflammatory responses to secondary stimuli, leading to cognitive impairments.

293 citationstop 1%

mousebulk RNA-seq

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