Tania Contente‐Cuomo

Analyzing the positioning and nucleotide sequence at fragment ends in plasma DNA may enable cancer diagnostics.

This study characterizes urine cfDNA fragmentation patterns and shows they reflect sub-nucleosomal organization, with potential for cancer diagnostics.

This study demonstrates the feasibility of ctDNA analysis in dogs with hemangiosarcoma using shallow whole genome sequencing, showing higher ctDNA fractions in malignant tumors compared to benign ones.

A personalized ctDNA test achieves high accuracy for residual disease detection after neoadjuvant therapy in breast cancer.

The paper evaluates pre-analytical factors affecting plasma DNA analysis by comparing DNA extraction methods and blood collection tubes using a multiplexed ddPCR assay.