Thomas Michael Maynard

platpy provides a spatial-first framework for analyzing spatial transcriptomic data, improving efficiency and reducing errors in multi-layer spatial analysis.

This study shows NAC treatment improves LgDel 22q11.2 deletion syndrome mouse cortical neurons' growth and connectivity without restoring wild-type gene expression or cell states.

This study identifies transient disruptions in progenitor states and layer 2/3 neuron generation in the frontal cortex of a 22q11DS mouse model, linking these changes to schizophrenia risk.

The paper defines the temporal and spatial lineage of progenitor populations in the developing mouse olfactory epithelium, showing how distinct precursor identities generate diverse cell types.