Author

April Stempien‐Otero

University of WashingtonORCID 0000-0001-6976-6512Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Alexander M. LoibeniD· 1 shared Ashley MckinstryiD· 1 shared Charles E. MurryiD· 1 shared Clayton E. FriedmaniD· 1 shared Dania Ahmed· 1 shared Douglas M. FowleriD· 1 shared Erica C. JonliniD· 1 shared Kai‐Chun YangiD· 1 shared

Activity by Year

2023-2023 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperGenetics

Alexander M. LoibenORCID

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1 paper

Recent·Most cited

GeneticsbioRxivPreprintJul 28, 2023

Multiplexed functional assessments of MYH7 variants in human cardiomyocytes at scale

Clayton E. Friedman, Shawn Fayer, Sriram Pendyala…·Kai‐Chun Yang

This study uses hiPSC-derived cardiomyocytes to assess MYH7 variants' effects, showing pathogenic variants reduce protein abundance and cell survival.

DOI 10.1101/2023.07.28.551073

humanCRISPR screen

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