Author

Ashley Mckinstry

University of WashingtonORCID 0009-0007-1776-9536Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:CRISPR screen· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:variant calling· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Alexander M. LoibeniD· 2 shared Charles E. MurryiD· 2 shared Clayton E. FriedmaniD· 2 shared Dania Ahmed· 2 shared Douglas M. FowleriD· 2 shared Kai‐Chun YangiD· 2 shared Lea M. StaritaiD· 2 shared Leslie S. Chao· 2 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersGenetics

Alexander M. LoibenORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

GeneticsbioRxivPreprintJul 28, 2023

Multiplexed functional assessments of MYH7 variants in human cardiomyocytes at scale

Clayton E. Friedman, Shawn Fayer, Sriram Pendyala…·Kai‐Chun Yang

This study uses hiPSC-derived cardiomyocytes to assess MYH7 variants' effects, showing pathogenic variants reduce protein abundance and cell survival.

DOI 10.1101/2023.07.28.551073

humanCRISPR screen

𝕏 PostBluesky

GeneticsJournal of Molecular and Cellular CardiologyPeer-reviewedApr 3, 2023

CRaTER enrichment for on-target gene-editing enables generation of variant libraries in hiPSCs

Clayton E. Friedman, Shawn Fayer, Sriram Pendyala…·Kai‐Chun Yang

CRaTER enriches for on-target gene-edited cells in hiPSCs, enabling efficient generation of variant libraries for studying cardiomyopathy-associated mutations.

12 citations

humanCRISPR screen

𝕏 PostBluesky