Author

Безпрозванный Илья Борисович

Peter the Great St. Petersburg Polytechnic UniversityORCID 0000-0001-7006-6951Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Alpaslan TasdoganiD· 1 shared Ashley Rowe· 1 shared Ashley SolmonsoniD· 1 shared Aundrea K. WestfalliD· 1 shared Brandon FaubertiD· 1 shared Bushra AfrozeiD· 1 shared Chen LingiD· 1 shared Dehui KongiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperGenetics

Alpaslan TasdoganORCID

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2 papers

Recent·Most cited

GeneticsJournal of Clinical InvestigationPeer-reviewedMar 17, 2026

L-2-hydroxyglutarate impairs neuronal differentiation through epigenetic activation of MYC expression

Wen Gu, Xun Wang, Ashley Solmonson…·Ralph J. DeBerardinis

This study shows that L-2HG accumulation due to L2HGDH deficiency impairs neuronal differentiation by epigenetically activating MYC, leading to stem cell self-renewal and reduced neuron formation.

3 citationstop 2%

humanbulk RNA-seq

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NeurosciencebioRxivPreprintSep 16, 2024

TRPC3 suppression ameliorates synaptic dysfunctions and memory deficits in Alzheimer's disease

Jiaxing Wang, Chen Ling, Zhengjun Wang…·Francesca‐Fang Liao

This study identifies TRPC3 as a therapeutic target for Alzheimer's disease by showing its role in synaptic dysfunction and memory deficits, with JW-65 as a potential inhibitor.

6 citations

mousehuman

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