Renato Morona

The paper identifies genes required for smooth lipopolysaccharide (S-LPS) production in E. coli K-12 through a genome-wide screen, revealing 27 mutants with defects in S-LPS production and highlighting the need for validation.

This study shows that weakening outer membrane-peptidoglycan interactions in E. coli enhances bile salt resistance by alleviating spatial constraints and reducing stress from UndPP-OAg intermediates.

This paper investigates tolerance mechanisms in bacterial polysaccharide synthesis pathways, showing that sharing a common substrate allows UndP recycling and enhances survival when one pathway is disrupted.