Xiaoxiang Hu

The paper maps a multi-layered molecular QTL atlas in chicken to understand complex trait regulation across tissues and developmental stages.

The paper identifies sex-specific genetic regulatory effects in chickens using whole-genome sequencing and transcriptomes, revealing sex-dependent gene regulation and structural variants.

The ChickenGTEx project provides a multi-tissue reference of regulatory variants in chicken, analyzing their functional impacts and utility in genetics, genomics, and evolutionary studies.

The paper presents PigGTEx, a resource linking genetic variants to transcriptomic phenotypes in pigs, showing pigs' similarity to humans in gene regulation and complex traits.

The paper introduces a large chicken reference panel with 13,187 genomes, showing improved imputation accuracy and statistical power for genome-wide association studies.

This study creates a LEPTIN-deficient pig model of NAFLD and shows that AMPK signaling plays a key role in hepatic fibrosis progression.

This study constructs a chicken pan-genome from 20 de novo assemblies, identifying novel genes predominantly in sub-telomeric regions that are undetectable by DNA sequencing but present in transcriptomes.

The paper uses low-coverage whole-genome sequencing in Duroc pigs to identify SNPs and perform GWAS, finding QTLs for teat number and back fat thickness.