George E. Liu

This study constructs a multi-tissue cell atlas of pigs, identifies cell-type-specific gene regulation, and links these to complex traits and human phenotypes.

GSOR and MTAO detect widespread cis-regulatory effects on bovine complex traits by linking gene expression with genetic scores and multi-trait associations.

The paper constructs a cattle cell-type-specific regulatory variant atlas by integrating bulk and single-cell RNA-seq data, identifying eQTL and linking them to GWAS loci for breeding insights.

The ChickenGTEx project provides a multi-tissue reference of regulatory variants in chicken, analyzing their functional impacts and utility in genetics, genomics, and evolutionary studies.

The paper performs a multi-breed meta-GWAS in pigs to identify genomic regions associated with complex traits and integrates with PigGTEx to prioritize variant-gene-tissue-trait circuits.

The paper constructs a sheep developmental gene expression atlas and identifies key genes associated with economically important traits by analyzing gene expression across developmental stages.

The paper presents PigGTEx, a resource linking genetic variants to transcriptomic phenotypes in pigs, showing pigs' similarity to humans in gene regulation and complex traits.

This study identifies selection signatures and loci associated with complex traits in pigs by analyzing multi-omics data from Eastern and Western breeds.

The paper quantifies how gene expression and splicing QTL explain heritability in cattle traits using Bayesian methods across 16 tissues.

The paper introduces a web server for multi-species transcriptome-wide association study (TWAS) analysis, enabling gene expression prediction and trait association in humans and farm animals.

This study identifies human functional variants with conserved effects in livestock species, showing their utility for understanding disease mechanisms.

The paper constructs a cattle Genotype-Tissue Expression atlas and identifies genetic regulatory variants linked to gene expression and traits in cattle.

The paper builds a TE atlas in pigs, showing young SINEs' roles in gene regulation, genetic diversity, and complex traits through multi-omics analysis.

The paper identifies and characterizes unknown porcine protein isoforms using tissue-based proteome maps and improves genome annotation.

The paper performs GWAS and fine-mapping on seven health traits in Holstein cattle to identify genetic variants and candidate genes associated with health outcomes.