Hongwei Holly Yin

High- versus low-dose dietary n-3 PUFA treatment produces mixed effects on DNA methylation and epigenetic fidelity in breast adipose tissue

This study examines how high- and low-dose n-3 PUFA treatments affect DNA methylation and epigenetic fidelity in breast adipose tissue, finding dose-specific and directionally discordant changes in promoter methylation.

Genomic Insights into the Demographic History and Local Adaptation of Wild Boars Across Eurasia

The paper analyzes whole-genome data from wild boars to trace their demographic history and identify genetic signatures of local adaptation in Central Asia.

The ChickenGTEx pilot analysis: a reference of regulatory variants across 28 chicken tissues

The ChickenGTEx project provides a multi-tissue reference of regulatory variants in chicken, analyzing their functional impacts and utility in genetics, genomics, and evolutionary studies.

Modeling cerebral development in vitro with L-MYC-immortalized human neural stem cell-derived organoids

This paper presents an organoid-based platform using L-MYC-immortalized human neural stem cells to model cerebral development in vitro, showing similar gene expression patterns to normal cortical development.

A compendium of genetic regulatory effects across pig tissues

The paper presents PigGTEx, a resource linking genetic variants to transcriptomic phenotypes in pigs, showing pigs' similarity to humans in gene regulation and complex traits.