Author

Ramith Hettiarachchi

Harvard UniversityORCID 0000-0001-7070-8213Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:protein sequence· 2 Research Focus:benchmarking· 1 Research Focus:database / resource· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Organism:multiple species· 1 Approach:optimal transport· 1 Research Focus:phylogenetics / evolution· 1

Frequent Co-Authors

Sergey OvchinnikoviD· 2 shared Adedolapo M. OjoawoiD· 1 shared Avi SwartziD· 1 shared Dorothee KerniD· 1 shared Gina El NesriD· 1 shared Hannah K. Wayment-SteeleiD· 1 shared Hasindu KariyawasamiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 16 mutual co-author links

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2 shared papersBiophysics

Sergey OvchinnikovORCID

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2 papers

Recent·Most cited

BiophysicsNaturePeer-reviewedAug 10, 2026

✦ In-depth digest

Learning millisecond protein dynamics from what is missing in NMR spectra

Hannah K. Wayment-Steele, Gina El Nesr, Ramith Hettiarachchi…·Dorothee Kern

Trained on missing NMR amide assignments in the Biological Magnetic Resonance Data Bank, Dyna-1 (ESM-3 layer 22 embeddings) predicts micro-to-millisecond conformational exchange seen in relaxation data.

16 citationstop 1%

multiple speciesprotein structure

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BioinformaticsbioRxivPreprintJul 23, 2023

Differentiable Search of Evolutionary Trees from Leaves

Ramith Hettiarachchi, Avi Swartz, Sergey Ovchinnikov

This paper introduces a differentiable method for inferring evolutionary trees from leaf nodes, achieving low error rates on up to 128 leaves.

DOI 10.1101/2023.07.23.550206

protein sequenceoptimal transport

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