Molecular BiologybioRxivPreprint
Yuanyang allele pairs enable engineered obligate co-inheritance for population replacement and suppression
Yunfei Li, Zhuangzhuang Qiao, Chunjie Xian…·Zhihui Zhu
The paper introduces YYAP, an engineered gene drive system that enforces obligate co-inheritance of alleles, demonstrating efficient population replacement and suppression in Drosophila.
DOI 10.1101/2025.11.14.688408