Markus G Stetter

Standing genetic variation drives polygenic adaptation to different environmental shifts

This study uses simulations to show how environmental shifts affect genetic adaptation, highlighting the role of standing genetic variation and using a CNN to predict environmental changes and mutation effects.

Adaptive Dynamics of Quantitative Traits in a SteadilyChanging Environment

This study investigates how environmental change speed and trait architecture influence adaptive dynamics using models and simulations, revealing critical thresholds and genetic equilibrium mechanisms.

Time series analysis in a maize landrace reveals rapid fixation of beneficial alleles

The paper analyzes a maize landrace selection experiment to identify loci under selection and track genetic changes over time.

The grain amaranth pangenome reveals domestication-associated changes in diversity and function of structural variation

The paper constructs a pangenome for grain amaranth, identifies structural variants, and links them to flowering time differences during domestication.

Pleiotropy and repeated mutation drove convergent domestication of grain amaranth

This study shows that repeated mutations in a single gene caused white seed color and reduced dormancy in domesticated amaranth, providing a competitive advantage in agricultural environments.

First Successful Targeted Mutagenesis Using CRISPR/Cas9 in Stably Transformed Grain Amaranth Tissue

The paper demonstrates targeted mutagenesis in grain amaranth using CRISPR/Cas9 and the CasCADE system to edit genes in the betalain biosynthesis pathway.

Domestication of the ancient grain Amaranthus cruentus L.

This study uses whole genome sequencing to identify the geographic origin and domestication centers of Amaranthus cruentus in North America, revealing three genomic groups and gene flow with its wild relative.

Domestication shaped the chromatin landscape of grain amaranth

The paper examines how domestication affects the chromatin landscape in grain amaranth, finding that 2.5% of chromatin regions switch states during domestication, associated with selective sweeps.

Going New Places: Successful Adaptation and Genomic Integrity of Grain Amaranth in India

This study examines the genetic adaptation of grain amaranth in India, finding comparable diversity to its native range and identifying genomic loci linked to climate adaptation.

Local selection shaped the diversity of European maize landraces

This study examines how maize introduction to Europe shaped genetic diversity and differentiation, finding landraces maintain high diversity despite selection pressures and modern breeding accumulating genetic load.

PopAmaranth: A population genetic genome browser for grain amaranths and their wild relatives

PopAmaranth provides a population genetic genome browser for grain amaranths and their wild relatives, enabling interdisciplinary research and crop improvement through accessible genetic variation analysis.

Comparative evolutionary analysis and prediction of deleterious mutation patterns between sorghum and maize

This study compares deleterious mutation patterns between sorghum and maize, finding sorghum diverges from the domestication cost hypothesis and develops a gene deleterious index with accuracy over 0.5.