Author

David J. Thornton

Manchester Academic Health Science CentreORCID 0000-0001-7148-1970Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:proteomics· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Angelica Castaneda· 1 shared Aynur Soenmez· 1 shared Bipasha ChakrabartyiD· 1 shared Callum David Holmes· 1 shared Denis L. J. LafontaineiD· 1 shared Emma N. HiltoniD· 1 shared Hilary L. AsheiD· 1 shared John R. P. KnightiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

Angelica Castaneda

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintOct 28, 2026

Stromal COL12A1 defines a pro-invasive extracellular matrix niche in appendiceal mucinous neoplasms and pseudomyxoma peritonei

Milly Upton, Raghavendar Thyagaraja Nagaraju, Angelica Castaneda…·PMPnet group

This study identifies stromal COL12A1 as a key component of the extracellular matrix niche that supports invasion in appendiceal mucinous neoplasms and pseudomyxoma peritonei.

DOI 10.64898/2026.10.26.761946

humanproteomics

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Molecular BiologybioRxivPreprintApr 1, 2025

AquIRE reveals multiple mechanisms of clinically induced RNA damage and the conservation and dynamics of glycoRNAs

Zijian Zhang, Zornitsa Vasileva Kotopanova, Kexin Dang…·John R. P. Knight

The paper develops AquIRE to quantify RNA damage and identifies multiple mechanisms of clinically induced RNA modifications, including glycoRNA dynamics across life kingdoms.

2 citations

experimental assay

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