Aynur Soenmez

Zα domain-dependent ZBP1 condensate formation induces an amyloidal necroptotic signalling complex

This study shows that ZBP1 condensate formation, driven by Z domain binding to Z-RNA, promotes necroptotic cell death to restrict HSV-1 infection.

AquIRE reveals multiple mechanisms of clinically induced RNA damage and the conservation and dynamics of glycoRNAs

The paper develops AquIRE to quantify RNA damage and identifies multiple mechanisms of clinically induced RNA modifications, including glycoRNA dynamics across life kingdoms.

Nucleolar stress controls mutant Huntingtin toxicity and monitors Huntington disease progression

This study shows that nucleolar stress affects mutant Huntingtin toxicity and progression in Huntington disease by altering rRNA maturation and NPM1 localization.

DNA isolation protocol effects on nuclear DNA analysis by microarrays, droplet digital PCR, and whole genome sequencing, and on mitochondrial DNA copy number estimation

The paper shows DNA isolation methods affect array CGH, ddPCR, and whole genome sequencing results in human brain tissue, with protocol-dependent biases in GC coverage and mtDNA copy number.