Author

Lande Vieira da Silva

Universidade Federal do Rio GrandeORCID 0000-0001-7158-0207Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Approach:simulation· 1

Frequent Co-Authors

Karina MachadoiD· 1 shared Nelson Dutra· 1 shared Pedro Eduardo Almeida da SilvaiD· 1 shared Terry P. LybrandiD· 1 shared

Activity by Year

2018-2018 · peak 1/yr

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4 top collaborators · 6 mutual co-author links

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1 shared paperBioinformatics

Karina MachadoORCID

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1 paper

Recent·Most cited

BioinformaticsbioRxivPreprintJun 5, 2018

Targeted Molecular Dynamics Simulations Suggest Direct Ligand Competition as a Plausible Efflux Inhibition Mechanism in the Multidrug Resistance Pump AcrB.

Lande Vieira da Silva, Pedro Eduardo Almeida da Silva, Karina Machado…·Terry P. Lybrand

The paper uses targeted molecular dynamics simulations to explore the transport mechanism of substrates in the AcrB multidrug resistance pump and suggests ligand competition as a potential efflux inhibition strategy.

2 citations

protein structuresimulation

𝕏 PostBluesky