Author

Pedro Eduardo Almeida da Silva

Universidade Federal do Rio GrandeORCID 0000-0003-1666-1295Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Approach:simulation· 1 Approach:statistical model· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Ana Júlia ReisiD· 1 shared Andréa von GrolliD· 1 shared Elis Regina Dalla CostaiD· 1 shared Fernanda Sá Spies· 1 shared Hermes Luís Neubauer de AmorimiD· 1 shared Karina MachadoiD· 1 shared Lande Vieira da SilvaiD· 1 shared Leonardo Souza EstevesiD· 1 shared

Activity by Year

2018-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperGenomics

Ana Júlia ReisORCID

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2 papers

Recent·Most cited

GenomicsTuberculosisPeer-reviewedOct 30, 2020

A highly rifampicin resistant Mycobacterium tuberculosis strain emerging in Southern Brazil

Maria Lúcia Rosa Rossetti, Pedro Eduardo Almeida da Silva, Richard Steiner Salvato…·Hermes Luís Neubauer de Amorim

The paper identifies a highly rifampicin-resistant Mycobacterium tuberculosis strain in Southern Brazil linked to a 12-nucleotide insertion in the rpoB gene and highlights its transmission among prison inmates.

9 citations

whole-genome sequencingstatistical model

𝕏 PostBluesky

BioinformaticsbioRxivPreprintJun 5, 2018

Targeted Molecular Dynamics Simulations Suggest Direct Ligand Competition as a Plausible Efflux Inhibition Mechanism in the Multidrug Resistance Pump AcrB.

Lande Vieira da Silva, Pedro Eduardo Almeida da Silva, Karina Machado…·Terry P. Lybrand

The paper uses targeted molecular dynamics simulations to explore the transport mechanism of substrates in the AcrB multidrug resistance pump and suggests ligand competition as a potential efflux inhibition strategy.

2 citations

protein structuresimulation

𝕏 PostBluesky