Author

Thomas F. Wulff

Max Planck Unit for the Science of PathogensORCID 0000-0001-7166-0899Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 1 Molecular Biology· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Emmanuelle CharpentieriD· 3 shared Karin Hahnke· 3 shared Katja SchmidtiD· 2 shared Knut FinstermeieriD· 2 shared Rina Ahmed-BegrichiD· 2 shared Alexander K. W. Elsholz· 1 shared Anne-Laure LécrivainiD· 1 shared Carolin J. SchifferiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersMicrobiology

Emmanuelle CharpentierORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Stress-induced ribosome degradation in Bacillus subtilis is mediated by the RNase Y-specificity complex

Fabián A. Cornejo, Kristina Driller, Rina Ahmed-Begrich, Katja Schmidt, Michael Jahn, Vivekanandan Shanmuganathan, Karin Hahnke, Florian Kondrot, Thomas F. Wulff, Sebastian Rämisch, Kathirvel Alagesan, Emmanuelle Charpentier, Kürşad Turgay

The paper identifies the Y-complex as a regulator of RNase Y specificity in Bacillus subtilis, showing it mediates stress-induced ribosome degradation by targeting rRNA.

Nature Communications · Jun 2, 2026Peer-reviewedMicrobiology

Dynamics of diversified A-to-I editing in Streptococcus pyogenes is governed by changes in mRNA stability

Thomas F. Wulff, Karin Hahnke, Anne-Laure Lécrivain, Katja Schmidt, Rina Ahmed-Begrich, Knut Finstermeier, Emmanuelle Charpentier

The paper identifies A-to-I editing in Streptococcus pyogenes, showing it diversifies and is regulated by mRNA stability in response to infection-related stimuli.

Nucleic Acids Research · Jul 25, 2024Peer-reviewedMolecular Biology

Expanding the genetic toolbox for the obligate human pathogen Streptococcus pyogenes

Nina Lautenschläger, Katja Schmidt, Carolin J. Schiffer, Thomas F. Wulff, Karin Hahnke, Knut Finstermeier, Moïse Mansour, Alexander K. W. Elsholz, Emmanuelle Charpentier

This study develops a comprehensive genetic toolbox for Streptococcus pyogenes, including plasmids, promoters, and reporters, to facilitate gene function studies and virulence mechanism analysis.

Frontiers in Bioengineering and Biotechnology · Jun 7, 2024Peer-reviewedSynthetic Biology